Giants’ Saquon Barkley out 3 weeks with an ankle sprain

According to a report from ESPN’s Adam Schefter, New York Giants star running back Saquon Barkley is going to be out for three weeks after an MRI today revealed an “ordinary” ankle sprain.

Barkley was injured in New York’s 31-28 comeback win at Arizona. The Giants trailed 20-0 at halftime and rallied from a 28-7 deficit with less than four minutes remaining in the third quarter. However, the Cardinals still covered the spread as 4.5-point home underdogs to improve to 2-0 ATS.

Barkley had 63 rushing yards and one touchdown on 17 carries before being getting injured in the fourth quarter. He also had six catches for 29 yards and one TD.

The Giants’ next three games are at San Francisco (Thursday), vs. Seattle (Monday Night Football) and at Miami.

Barkley had 51 rushing yards on 12 attempts in New York’s 40-0 season-opening loss to Dallas as a 3.5-point home underdog. He had three receptions for 12 receiving yards against the Cowboys.

Barkley is off his best season since his rookie campaign in 2018. He had a career-high 1,312 rushing yards, 10 TDs and a 4.4 yards-per-carry average. Barkley also had 57 catches for 338 yards in 2022.

As of late Monday afternoon, most books had the 49ers installed as 10.5-point home favorites Thursday night vs. New York. The total was 45 points, while the Giants were +400 (Caesars) to +430 (Circa) on the money line.

Brian Daboll’s team is 1-1 straight up and 0-2 ATS.