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| not really a fan of it, but smoked it in the 60's in the Haight with my good friend and nextdoor neighbor Barefoot John of the P.H. Phactor Jugband watching the fog roll in from the roof of his house on Clayton St ... dymethal-triptamine (sp) ... and as i recall being told it was used for developing film? probably not the best thing for the braincells over an extended period of time. go back to weed
__________________ no matter where you go, there you are ... "Every step, a fuckin' adventure."..-Al Swearengen Gyps ![]() 'Playoff bound - next year' ......... |
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__________________ "When I'm there, I'm not here. I can't talk about my singing; I'm inside it. How can you describe something you're inside of?" |
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| Albert Hofmann, 102; Swiss chemist discovered LSD - Los Angeles Times ![]() Albert Hofmann was a synthetic chemist with Sandoz Laboratories, now Novartis, in Switzerland when in 1943 he stumbled on the hallucinatory effects of LSD. After it became seen by Harvard's Timothy Leary and others in the '60s as a pathway to spiritual enlightenment, and then as a major recreational drug, “Instead of a ‘wonder child,’ LSD suddenly became my ‘problem child,’ ” Hofmann said. By Thomas H. Maugh II, Los Angeles Times Staff Writer 4:39 PM PDT, April 29, 2008 Albert Hofmann, the Swiss chemist who discovered LSD and thereby gave the psychedelic generation the pharmaceutical vehicle to turn on, tune in and drop out, has died. He was 102. Hofmann died this morning at his home in Basel of a heart attack, according to Rick Doblin, the head of MAPS, the Multidisciplinary Assn. for Psychedelic Studies. Hofmann also identified and synthesized the active ingredients of peyote mushrooms and a Mexican psychoactive plant called ololiuqui and developed at least three related, non-psychoactive compounds that became widely used in medicine. Those other feats would have been little remembered, however, had he not accidentally gotten a trace amount of an experimental compound called lysergic acid diethylamide on his fingertips and taken the world's first acid trip. Hofmann was a talented synthetic chemist working in the Basel research center of Sandoz Laboratories -- now Novartis -- in the 1930s when he began studying the chemistry of ergot, the common name for a fungus that grows on rye, barley and certain other plants. Although ergot is poisonous, midwives had used a crude extract for centuries to induce labor in pregnant women. Twenty years earlier, researchers had isolated ergotamine, the first ergot alkaloid isolated in pure form, and the compound had become widely used for halting bleeding after childbirth and as a treatment for migraine headaches. In the early 1930s, American researchers had identified the primary active ingredient of ergot, a chemical called lysergic acid. Hofmann devised a technique to make a series of derivatives of lysergic acid called amides and began systematically looking for medically useful compounds. The twenty-fifth compound he synthesized, in 1938, was lysergic acid diethylamide (in German, lyserg-saure-diathylamid), or LSD-25. Because this compound had a chemical structure similar to an existing drug called Coramine, Hofmann had hoped that it would be a stimulant for the respiratory and circulatory systems. But testing in experimental animals showed no significant activity for the drug -- although the animals were observed to become restless after its administration -- and it was abandoned. During this period, Hofmann synthesized at least three amides that became drugs: Methergine, which is used to halt bleeding after birth; Hydergine, which improves circulation in the limbs and cerebral function in the elderly; and Dihydergot, which is used to stabilize circulation and blood pressure. Prompted by what Hofmann later described as a "peculiar presentiment" that LSD-25 might have properties other than those established in the first investigations, he decided to look at it again. On Friday afternoon, April 16, 1943, Hofmann had just completed synthesizing a new batch when, he subsequently wrote his supervisor, "I was forced to interrupt my work in the laboratory in the middle of the afternoon and proceed home, being affected by a remarkable restlessness, combined with slight dizziness. "At home, I lay down and sank into a not-unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination. In a dreamlike state I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours, this condition faded away." Hofmann suspected that the state had been caused by something in the lab. In an interview on his 100th birthday, he said, "I didn't know what caused it, but I knew that it was important." After breathing the solvents he had used produced no effect, Hofmann suspected that the synthetic drug was the source. "LSD spoke to me," he said. "He came to me and said, 'You must find me.' He told me, 'Don't give me to the pharmacologist, he won't find anything.' " The following Monday, he took what he considered to be an extremely small dose of LSD, so small that a similar dose of even the most powerful toxin known at the time would have had little or no effect. He had planned to gradually increase the dosage, but instead was surprised to encounter the first bad acid trip. Feeling bad, he asked his laboratory assistant to accompany him home on his bicycle, no cars being available because of wartime restrictions. During the trip, "I had the feeling that I could not move from the spot. I was cycling, cycling, but the time seemed to stand still." By the time they reached his home, its furnishings had transformed themselves into terrifying objects. "Everything in the room spun around, and the familiar objects and pieces of furniture assumed grotesque, threatening forms," he wrote in his autobiography, "LSD -- My Problem Child." "They were in constant motion, animated, as if driven by an inner restlessness. The lady next door [became] a malevolent, insidious witch with a colored mask." Hofmann thought he was dying and sent for a doctor, but the physician could find nothing wrong. After about six hours, the experience began to change into a pleasant one. "After some time, with my eyes closed, I began to enjoy this wonderful play of colors and forms, which it really was a pleasure to observe. Then I went to sleep and the next day I was fine. I felt quite fresh, like a newborn." That day, April 19, has subsequently been celebrated by LSD proponents as "Bicycle Day." thomas.maugh@latimes.com
__________________ minnow@ majorwager.com |
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__________________ minnow@ majorwager.com |
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Dude... lol i forgot i even bought this shit....Just found the bottle/vial hidden in one of my shoes in the closet... Everything seems pretty calm and quiet here tonight....I may go ahead and give this shit a try. I've had 5 or 6 drinks tonight though... will that fuck this up? I'm still sober....I just know my face is already a little numb...not sure how this stuff interacts with liquor. |
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well, i thought Trish was asleep, but, she's still sitting up doing shit on the other comp. had a few more drinks now, so, probably best wait till morning to hit this shit...lol actually, probably better for everyone if i wait till daylight..... ![]() |
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| lol Yep, thats the one. Just walked in and acted like i was looking for the remote, and she's out like a light....Phones are off, and doors are bolted...I'm all set, except for a helmet.. Gonna turn this thing off too for a bit...I've made the mistake of posting when i'm out of wack before... ![]() |
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| Shit man....You can have that Salvia shit....That ain't my thing at all. One positive is, i did sleep good. The negatives far outweigh the positive though, imo. I'll stick to safe, healthy drug and drinking habits....Like x, acid, weed and coke, bourbnon and absinthe. All of which i could combine, and binge on tonight...And not feel as fuckin loopy and tarded out as i did last night. |
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__________________ no matter where you go, there you are ... "Every step, a fuckin' adventure."..-Al Swearengen Gyps ![]() 'Playoff bound - next year' ......... |
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